GLDC anticorps (N-Term)
Aperçu rapide pour GLDC anticorps (N-Term) (ABIN952523)
Antigène
Voir toutes GLDC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 56-85, N-Term
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Specificité
- This antibody recpognizes Human and Mouse GLDC (N-term).
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Purification
- Protein A column, followed by peptide affinity purification
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Immunogène
- KLH conjugated synthetic peptide between 56~85 amino acids from the N-terminal region of Human GLDC
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GLDC (Glycine Dehydrogenase (GLDC))
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Autre désignation
- GLDC
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Sujet
- Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).Synonyms: GCSP, Glycine cleavage system P protein, Glycine decarboxylase, Glycine dehydrogenase [decarboxylating], mitochondrial
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Poids moléculaire
- 112730 Da
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ID gène
- 2731
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NCBI Accession
- NP_000161
Antigène
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